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CD45 Rabbit Polyclonal Antibody

CAT: 0992-ER1902-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1902-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
CAS Number
9007-83-4
Product Name Alternative
B220 antibody CD 45 antibody CD45 antibody CD45 antigen antibody CD45R antibody GP180 antibody L-CA antibody LCA antibody Leukocyte common antigen antibody loc antibody Ly-5 antibody LY5 antibody Ly5, homolog of antibody Lyt-4 antibody OTTHUMP00000033813 antibody OTTHUMP00000033816 antibody OTTHUMP00000033817 antibody OTTHUMP00000038574 antibody Protein tyrosine phosphatase receptor type c polypeptide antibody Protein tyrosine phosphatase, receptor type C antibody protein tyrosine phosphatase, receptor type, C antibody Protein tyrosine phosphatase, receptor type, c polypeptide antibody Ptprc antibody PTPRC_HUMAN antibody Receptor-type tyrosine-protein phosphatase C antibody T200 antibody T200 glycoprotein antibody T200 leukocyte common antigen antibody
Abbreviation
PTPRC
Swiss Prot
P08575 Human
Cellular Locus
Cell membrane, membrane raft.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human CD45 aa 1-60.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
U937 cell lysates, Jurkat cell lysates, Jurkat.
Concentration
1 mg/mL
Dilution
WB:1:500-1:1,000 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size 147 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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