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CACNG2 Rabbit Polyclonal Antibody

CAT: 0992-ER1901-89Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-89Size:100 µL
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Description
Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein that in humans is encoded by the CACNG2 gene. L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which having been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. Stargazin is involved in the transportation of AMPA receptors to the synaptic membrane, and the regulation of their receptor rate constants — via its extracellular domain — once it is there. As it is highly expressed throughout the cerebral cortex, it is likely to have an important role in learning within these areas, due to the importance of AMPA receptors in LTP.
CAS Number
9007-83-4
Product Name Alternative
AW060990 antibody B230105C07Rik antibody B930041E13Rik antibody Cacng2 antibody Calcium channel voltage dependent gamma subunit 2 antibody CaV gamma 2 antibody CCG2_HUMAN antibody Ipr328 antibody MGC123981 antibody MGC138502 antibody MGC138504 antibody Neuronal voltage gated calcium channel gamma 2 subunit antibody Neuronal voltage-gated calcium channel gamma-2 subunit antibody Stargazer antibody stg antibody TARP gamma-2 antibody Transmembrane AMPAR regulatory protein gamma-2 antibody Voltage dependent calcium channel gamma 2 subunit antibody Voltage-dependent calcium channel gamma-2 subunit antibody Wag antibody Waggler antibody
Abbreviation
Voltage-dependent calcium channel gamma-2 subunit,Neuronal voltage-gated calcium channel gamma-2 subunit,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2,CACNG2
Swiss Prot
Q9Y698 Human, O88602 Mouse, Q71RJ2 Rat
Cellular Locus
Cell junction, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human CACNG2 aa 196-245 / 323.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Mouse cerebellum tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, A549, SHSY5Y, mouse brain tissue, rat Cerebellum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2000;IHC-P: 1;50-1:200;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 36 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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