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B3GAT1 Rabbit Polyclonal Antibody

CAT: 0992-ER1901-83Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-83Size:100 µL
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Description
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (B3GAT1) is an enzyme that in humans is encoded by the B3GAT1 gene, whose enzymatic activity creates the CD57 epitope on other cell surface proteins. In immunology, the CD57 antigen (CD stands for cluster of differentiation) is also known as HNK1 (human natural killer-1) or LEU7. It is expressed as a carbohydrate epitope that contains a sulfoglucuronyl residue in several adhesion molecules of the nervous system. The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. In anatomical pathology, CD57 (immunostaining) is similar to CD56 for use in differentiating neuroendocrine tumors from others. There is an increase in the number of circulating CD57 positive cells in the blood of patients who have recently undergone organ or tissue transplants, especially of the bone marrow, and in patients with HIV.
CAS Number
9007-83-4
Product Name Alternative
3-glucuronyltransferase 1 antibody 3-glucuronyltransferase antibody B3GA1_HUMAN antibody B3gat1 antibody Beta 1 3 glucuronyltransferase 1 antibody Beta-1 antibody Beta-1,3-glucuronyltransferase 1 antibody CD 57 antibody CD57 antibody CD57 antigen antibody Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1 antibody Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 antibody GlcAT P antibody GlcAT-P antibody GLCATP antibody GlcUAT P antibody GlcUAT-P antibody GlcUATP antibody Glucuronosyltransferase P antibody HNK 1 antibody HNK1 antibody LEU 7 antibody LEU7 antibody LEU7 antigen antibody NK 1 antibody NK1 antibody UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase antibody UDP-GlcUA:glycoprotein beta-1 antibody
Abbreviation
GlcAT-P, GlcUAT-P, B3GAT1, GLCATP,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,glycoprotein beta-1,3-glucuronyltransferase,Glucuronosyltransferase P,Beta-1,3-glucuronyltransferase 1
Swiss Prot
Q9P2W7 Human, Q9CW73 Mouse, O35789 Rat
Cellular Locus
Golgi apparatus membrane, Secreted, extracellular region.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human B3GAT1 aa 285-334 / 334.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
293 cell lysates, F9, SHSY5Y, Rat brain tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:100 ;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 38 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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