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Dux Rabbit Polyclonal Antibody

CAT: 0992-ER1901-52Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-52Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The double homeobox (DUX) proteins are encoded by 3.3-kilobase repeats found throughout the human genome. The DUX family includes DUX1, DUX2, DUX3, DUX4 and DUX5. Each of these family members, excluding DUX2, contains two homeobox domains. DUX2 contains only one homeobox domain. DUX1 and DUX5 are identical to one another and they share 98% identity with DUX3 and approximately 70% identity with DUX2. The genes encoding DUX5 and DUX3 both contain additional start sites that result in N-terminal extended isoforms. The homeodomains found in DUX5 and DUX1 are similar to those found in Pax-3, Pax-7, OTX1 and OTX2. DUX4, also known as DUX10, is capable of forming homodimers. In addition, the gene encoding DUX4 maps within the D4Z4 repeat unit that has been implicated in Facioscapulohumeral muscular dystrophy (FSHD).
CAS Number
9007-83-4
Product Name Alternative
Double homeobox 4 antibody Double homeobox protein 10 antibody Double homeobox protein 4 antibody Double homeobox protein 4/10 antibody DUX10 antibody DUX4L antibody DUX4L1 antibody
Abbreviation
Dux
Swiss Prot
Q9UBX2 Human, A1JVI8 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within mouse Dux aa 247-486 / 674.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Hela cell lysate, Jurkat cell lysate, Raji cell lysates, rat testis tissue, mouse testis tissue, MG-63.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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