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KCNAB1 Rabbit Polyclonal Antibody

CAT: 0992-ER1901-34Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1901-34Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Modulates action potentials via its effect on the pore-forming alpha subunits (Probable). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the closure of KCNA1, KCNA2 and KCNA5 channels. Accelerates KCNA4 channel closure. Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4. Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6. Enhances KCNB1 and KCNB2 channel activity (By similarity). Binds NADPH; this is required for efficient down-regulation of potassium channel activity. Has NADPH-dependent aldoketoreductase activity. Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.
CAS Number
9007-83-4
Product Name Alternative
hKvb3 antibody hKvBeta3 antibody K (+) channel subunit beta-1 antibody KCAB1_HUMAN antibody KCNA1B antibody KCNAB1 antibody Kv-beta-1 antibody Kvb1.3 antibody Voltage-gated potassium channel beta-1 subunit antibody Voltage-gated potassium channel subunit beta-1 antibody
Abbreviation
Kcnab1
Swiss Prot
Q14722 Human, P63143 Mouse, P63144 Rat
Cellular Locus
Cell membrane, cytoplasm, membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within mouse KCNAB1 aa 36-85 / 401.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Mouse brain tissue lysate, rat brain tissue lysate, rat cerebellum tissue lysate, EA.hy926, rat testis tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB:1:500-1:2,000;IF-Cell:1:50-1:100;IHC-P:1:50-1:200;FC:1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46.5 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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