Galectin 3 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-82Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-ER1803-82Size:100 µL
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Description
Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of β1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn's disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.
CAS Number
9007-83-4
Product Name Alternative
35 kDa lectin antibody Carbohydrate binding protein 35 antibody Carbohydrate-binding protein 35 antibody CBP 35 antibody CBP35 antibody Gal-3 antibody GAL3 antibody Galactose-specific lectin 3 antibody Galactoside-binding protein antibody GALBP antibody Galectin 3 internal gene,included antibody Galectin-3 antibody Galectin3 antibody GALIG antibody GBP antibody IgE binding protein antibody IgE-binding protein antibody L 31 antibody L 34 antibody L-31 antibody L-34 galactoside-binding lectin antibody L31 antibody Laminin-binding protein antibody Lectin L-29 antibody Lectin, galactose binding, soluble 3 antibody LEG3_HUMAN antibody LGALS2 antibody LGALS3 antibody MAC 2 antigen antibody Mac-2 antibody Mac-2 antigen antibody MAC2 antibody Macrophage galactose-specific lectin antibody MGC105387 antibody
Abbreviation
Gal-3, CBP 35, GALBP, LGALS3
Swiss Prot
P17931 Human, P16110 Mouse, P08699 Rat
Cellular Locus
Cytoplasm, Nucleus, Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Galectin 3 aa 1-180.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
SiHa, mouse colon tissue, A431, LOVO, rat lung tissue, human colon cancer tissue, mouse testis tissue.
Concentration
1 mg/mL
Dilution
WB:1:500;IF-Cell:1:50-1:200;IHC-P:1:50-1:200;FC:1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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