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HEC1 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-56Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-56Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene. Ndc80 is one of the proteins of outer kinetochore. It forms a heterotetramer with proteins NUF2, SPC25, and SPC24. This protein complex has microtubule-binding domains. HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
CAS Number
9007-83-4
Product Name Alternative
from Entrez Gene ; antibody HEC antibody Highly expressed in cancer antibody Highly expressed in cancer protein antibody Highly expressed in cancer rich in leucine heptad repeats antibody HsHec1 antibody hsNDC80 antibody Kinetochore associated 2 antibody Kinetochore associated protein 2 antibody Kinetochore protein Hec1 antibody Kinetochore protein NDC80 homolog antibody Kinetochore-associated protein 2 antibody KNTC2 antibody ndc80 antibody NDC80 homolog kinetochore complex component antibody NDC80 kinetochore complex component homolog antibody NDC80, S. cerevisiae, homolog of antibody NDC80_HUMAN antibody Retinoblastoma associated protein HEC antibody Retinoblastoma-associated protein HEC antibody TID3 antibody
Abbreviation
HsHec1, NDC80, HEC, HEC1, KNTC2
Swiss Prot
O14777 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human HEC1 aa 300-505 / 642.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
SiHa cell lysates, HL-60 cell lysates, MG-63.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 74 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No