CACNA1C Rabbit Polyclonal Antibody

CACNA1C Rabbit Polyclonal Antibody

• Description: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group (Probable).
• Product Name Alternative: alpha-1 polypeptide antibody cardiac muscle antibody isoform 1 antibody L type antibody CAC1C_HUMAN antibody CACH 2 antibody CACH2 antibody CACN 2 antibody CACN2 antibody CACNA1C antibody CACNL1A1 antibody Calcium channel antibody Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody Calcium channel voltage dependent L type alpha 1C subunit antibody CaV1.2 antibody CCHL1A1 antibody DHPR alpha 1 antibody DHPR alpha 1 subunit antibody LQT8 antibody TS antibody Voltage dependent L type calcium channel alpha 1C subunit antibody Voltage dependent L type calcium channel subunit alpha 1C antibody Voltage gated calcium channel alpha subunit Cav1.2 antibody Voltage gated calcium channel subunit alpha Cav1.2 antibody Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* antibody Voltage-dependent L-type calcium channel subunit alpha-1C antibody Voltage-gated calcium channel subunit alpha Cav1.2 antibody
• Abbreviation: CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
• CAS Number: 9007-83-4
• Swiss Prot: Q13936 Human, Q01815 Mouse, P22002 Rat
• Cellular Locus: Plasma membrane.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within mouse CACNA1C aa 802-851 / 2,139.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: Dot Blot, IF-Cell, IHC-P, FC
• Positive Control: SiHa, SKOV-3, rat brain tissue, human kidney tissue, human uterus tissue, mouse heart tissue.
• Concentration: 1 mg/mL
• Dilution: Dot Blot: 1:500-1:1,000;IF-Cell: 1:500-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 249 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No