RYR2 Rabbit Polyclonal Antibody

Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

9007-83-4

Arrhythmogenic right ventricular dysplasia 2 antibody ARVC2 antibody ARVD2 antibody Brain ryanodine receptor calcium release channel antibody Brain type ryanodine receptor antibody Cardiac muscle ryanodine receptor calcium release channel antibody Cardiac muscle type ryanodine receptor antibody CCO antibody Central core disease of muscle antibody HBRR antibody hRYR 2 antibody hRYR2 antibody MHS antibody MHS1 antibody Ryanodine receptor 1 (skeletal) antibody Ryanodine receptor 1 antibody Ryanodine receptor 2 (cardiac) antibody Ryanodine receptor 2 antibody Ryanodine receptor 3 antibody Ryanodine receptor type1 antibody RYDR antibody RYR 1 antibody RYR 2 antibody RYR 3 antibody RYR antibody RYR-1 antibody RyR1 antibody RYR1_HUMAN antibody RYR2 antibody RYR3 antibody Sarcoplasmic reticulum calcium release channel antibody Skeletal muscle calcium release channel antibody Skeletal muscle ryanodine receptor antibody Skeletal muscle type ryanodine receptor antibody Skeletal muscle-type ryanodine receptor antibody SKRR antibody Type 1 like ryanodine receptor antibody Type 1 ryanodine receptor antibody VTSIP antibody

RYR-2, RyR2, hRYR-2, RYR2

Q92736 Human, E9Q401 Mouse, B0LPN4 Rat

Membrane. Sarcoplasmic reticulum.

Synthetic peptide within Human RYR2 aa 1,471-1,520 / 4,967.

Non-conjugated

Rabbit polyclonal Antibody

WB, IF-Cell, IHC-P, FC

293T, LOVO, SH-SY-5Y, Siha, human fetal skeletal muscle tissue, mouse brain tissue, mouse cerebellum tissue, rat skeletal muscle tissue.

1 mg/mL

WB: 1:500;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Immunogen affinity purified.

Liquid

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

565 kDa

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.