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DDIT3 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-20Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-20Size:100 µL
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Description
DDIT3 also named GADD 153 which has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from "classical" C/EBP binding sites, recognizing instead unique "nonclassical" sites. Thus GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells, similar to the regulatory function of Id on the activity of Myo D and Myo D-related proteins involved in the development of muscle cells.
CAS Number
9007-83-4
Product Name Alternative
C/EBP homologous protein antibody C/EBP Homology Protein antibody C/EBP zeta antibody C/EBP-homologous protein 10 antibody C/EBP-homologous protein antibody CCAAT/enhancer binding protein homologous protein antibody CEBPZ antibody CHOP 10 antibody CHOP antibody CHOP-10 antibody CHOP10 antibody DDIT 3 antibody DDIT-3 antibody Ddit3 antibody DDIT3_HUMAN antibody DNA Damage Inducible Transcript 3 antibody DNA damage-inducible transcript 3 protein antibody GADD 153 antibody GADD153 antibody Growth Arrest and DNA Damage Inducible Protein 153 antibody Growth arrest and DNA damage inducible protein GADD153 antibody Growth arrest and DNA damage-inducible protein GADD153 antibody MGC4154 antibody
Abbreviation
DDIT-3, CHOP, CHOP-10, DDIT3, CHOP, CHOP10, GADD153
Swiss Prot
P35638 Human, P35639 Mouse
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human DDIT3 aa 60-130
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, FC
Positive Control
Mouse brain tissue lysate, LOVO, mouse testis tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 19 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No