NDRG2 Rabbit Polyclonal Antibody
CAT:
992-ER1802-94
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NDRG2 Rabbit Polyclonal Antibody
- Description: The N-myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65% homology. NDRG2 (NDRG family member 2), also known as SYLD, is a 371 amino acid protein that localizes to both the cytoplasm and the perinuclear region in neurons. Expressed at high levels in heart, brain, dendritic cells, salivary gland and skeletal muscle and at lower levels in liver and kidney, NDRG2 is thought to be involved in dendritic and neuronal cell differentiation and outgrowth. Additionally, NDRG2 expression is downregulated in a variety of carcinomas, including liver cancer, pancreatic cancer and meningioma, suggesting a possible role for NDRG2 in tumor suppression. NDRG2 is found in brain lesions of Alzheimer Disease (AD)-affected patients and is thought to be associated with the progression of AD. Five isoforms of NDRG2 exist due to alternative splicing events.
- Product Name Alternative: Antidepressant related protein ADRG123 antibody Cytoplasmic protein Ndr1 antibody DKFZp781G1938 antibody FLJ25522 antibody KIAA1248 antibody N myc downstream regulated gene 2 antibody N myc downstream regulator 2 antibody NDR1 related protein NDR2 antibody NDRG 2 antibody NDRG family member 2 antibody NDRG1 related protein antibody NDRG2 antibody NDRG2_HUMAN antibody Protein NDRG2 antibody Protein Syld709613 antibody SYLD antibody Syld709613 protein antibody
- Abbreviation: NDRG2, KIAA1248, SYLD
- CAS Number: 9007-83-4
- Swiss Prot: Q9UN36 Human, Q9QYG0 Mouse, Q8VBU2 Rat
- Cellular Locus: Cytoplasm.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Recombinant protein within Human NDRG2 aa 13-160 / 371.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IHC-P, FC
- Positive Control: Mouse brain tissue, mouse skeletal muscle tissue, rat brain tissue, human liver tissue, human prostate tissue.
- Concentration: 1 mg/mL
- Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:100 ;FC: 1:50-1:100
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: 41 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No