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TAK1 Rabbit Polyclonal Antibody

CAT: 0992-ER1802-90Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1802-90Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 is a protein with intrinsic kinase activity towards serine/ threonine residues and that is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase sup-pressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFβ-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFβ stimulation.
CAS Number
9007-83-4
Product Name Alternative
M3K7_HUMAN antibody MAP3K 7 antibody Map3k7 antibody MEKK7 antibody Mitogen activated protein kinase kinase kinase 7 antibody Mitogen-activated protein kinase kinase kinase 7 antibody TAK1 antibody TGF beta activated kinase 1 antibody TGF-beta-activated kinase 1 antibody TGF1a antibody Transforming growth factor beta activated kinase 1 antibody Transforming growth factor-beta-activated kinase 1 antibody
Abbreviation
TGF-beta-activated kinase 1, MAP3K7, TAK1
Swiss Prot
O43318 Human, Q62073 Mouse, P0C8E4 Rat
Cellular Locus
Cell membrane, Cytoplasm, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human TAK1 aa 560 to the C-terminus.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
MCF-7, N2A, SH-SY-5Y, rat brain tissue, human breast tissue, mouse prostate tissue, K562.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 67 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No