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RBX1 Rabbit Polyclonal Antibody

CAT: 0992-ER1802-9Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1802-9Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rbx1 (also designated ROC1 and Hrt1) and the closely related protein Rbx2 (also designated ROC2) are RING finger containing homologs of the yeast protein APC11, a member of the anaphase-promoting complex (APC). Rbx1 was shown to be a component of the von Hippel-Lindau (VHL) transcription elongation complex, which includes VHL, Elongin B, Elongin C and Cullin-2. Rbx1 interacts with Cullin-1 in the SCF (Skp1-Cdc53-F-box protein) ubiquitin ligase complex (2-4). Rbx1 functions as a common subunit of SCF complexes required for ubiquination of various proteins including yeast G1 cyclins, IkBa and b-catenin (2-4). Rbx1 was shown to enhance the ubiquitin ligase activity of the VHL/Cullin-2 complex, and of the SCF/Cullin-1 complex.
CAS Number
9007-83-4
Product Name Alternative
BA554C12.1 antibody E3 ubiquitin-protein ligase RBX1 antibody FLJ60363 antibody MGC13357 antibody MGC1481 antibody OTTHUMP00000028983 antibody Protein ZYP antibody Rbx 1 antibody Rbx1 antibody RBX1_HUMAN antibody Regulator of cullins 1 antibody Ring box 1 antibody Ring box 1 E3 ubiquitin protein ligase antibody RING box protein 1 antibody RING finger protein 75 antibody RING finger protein antibody RING-box protein 1 antibody Ringbox protein 1 antibody RNF 75 antibody RNF75 antibody ROC 1 antibody ZYP protein antibody
Abbreviation
Rbx1, RBX1, RNF75, ROC1
Swiss Prot
P62877 Human, P62878 Mouse
Cellular Locus
Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human RBX1 aa 1-108 / 108.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
HepG2 cell lysate, 293T, MCF-7, human colon cancer tissue, human stomach cancer tissue, mouse colon tissue, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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