BCHE Rabbit Polyclonal Antibody

BCHE Rabbit Polyclonal Antibody

• Description: Present in most cells except erythrocytes, butyrylcholine esterase (BChE), also designated acylcholine acylhydrolase or pseudocholinesterase, has esterase activity as well as aryl acylamidase activity. It hydrolyzes acylcholine into choline and carboxylate. BChE is synthesized in the liver and is highly reactive with organophosphate esters. BChE can form a homotetramer composed of two dimers linked by a disulfide bond. Defects in the gene encoding BChE are associated with the disease hypocholinesterasemia. Inhibition of BChE effects the toxicity of organophosphates in the respiratory system suggesting that BChE may play a role in respiratory function. In addition, BChE may play an important pharmocological role by hydrolyzing toxic esters. This suggests an involvement of BChE in a treatment for intoxication with substances such as cocaine.
• Product Name Alternative: Acylcholine acylhydrolase antibody BCHE antibody Butyrylcholine esterase antibody CHE1 antibody CHE2 antibody CHLE_HUMAN antibody Choline esterase II antibody Cholinesterase (serum) 2 antibody Cholinesterase 1 antibody Cholinesterase antibody E1 antibody Pseudocholinesterase antibody Pseudocholinesterase E1 antibody
• Abbreviation: BCHE, CHE1
• CAS Number: 9007-83-4
• Swiss Prot: P06276 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within Human BCHE aa 309-520 / 602.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: Human blood plasma, HepG2, LOVO, human liver tissue, human colon cancer tissue, human skin tissue, human prostate tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 68 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No