BCHE Rabbit Polyclonal Antibody

CAT: 0992-ER1802-86Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-ER1802-86Size:100 µL
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Description
Present in most cells except erythrocytes, butyrylcholine esterase (BChE), also designated acylcholine acylhydrolase or pseudocholinesterase, has esterase activity as well as aryl acylamidase activity. It hydrolyzes acylcholine into choline and carboxylate. BChE is synthesized in the liver and is highly reactive with organophosphate esters. BChE can form a homotetramer composed of two dimers linked by a disulfide bond. Defects in the gene encoding BChE are associated with the disease hypocholinesterasemia. Inhibition of BChE effects the toxicity of organophosphates in the respiratory system suggesting that BChE may play a role in respiratory function. In addition, BChE may play an important pharmocological role by hydrolyzing toxic esters. This suggests an involvement of BChE in a treatment for intoxication with substances such as cocaine.
CAS Number
9007-83-4
Product Name Alternative
Acylcholine acylhydrolase antibody BCHE antibody Butyrylcholine esterase antibody CHE1 antibody CHE2 antibody CHLE_HUMAN antibody Choline esterase II antibody Cholinesterase (serum) 2 antibody Cholinesterase 1 antibody Cholinesterase antibody E1 antibody Pseudocholinesterase antibody Pseudocholinesterase E1 antibody
Abbreviation
BCHE, CHE1
Swiss Prot
P06276 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human BCHE aa 309-520 / 602.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Human blood plasma, HepG2, LOVO, human liver tissue, human colon cancer tissue, human skin tissue, human prostate tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 68 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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