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Rae1 Rabbit Polyclonal Antibody

CAT: 0992-ER1802-61Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1802-61Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mrnp41 (mRNA-binding protein, 41-KD), also known as Rae1 protein homolog and mRNA export factor, is a 368 amino acid protein that binds mRNA and is involved in nucleocytoplasmic transport. Though characterized in both the nucleus and cytoplasm, mrnp41 is primarily localized to the nuclear pore complex in the nuclear envelope. Mutations in mrnp41 may result in the accumulation of poly (A)-containing mRNA in the nucleus, further supporting the role of mrnp41 as a primary nuclear exporter of mRNA. Along with Nup98, mrnp41 has been shown to regulate E-cadherin, an activating subunit of the anaphase-promoting complex complex, which results in the prevention of securin degradation, therefore suggesting that mrnp41 may play a potential role in maintaining euploidy. Also, during mitosis, both mrnp41 and NuMA have been shown to be required for bipolar spindle formation.
CAS Number
9007-83-4
Product Name Alternative
dJ481F12.3 antibody dJ800J21.1 antibody FLJ30608 antibody Homolog of yeast Rae1 (Bharathi) mRNA associated protein of 41 kDa (Kraemer) antibody Homolog of yeast Rae1 mRNA associated protein of 41 kDa antibody MGC117333 antibody MGC126076 antibody MGC126077 antibody MIG 14 antibody MIG14 antibody Migration inducing gene 14 antibody Mnrp 41 antibody Mnrp41 antibody mRNA associated protein mrnp 41 antibody mRNA binding protein 41 kD antibody mRNA export factor antibody mRNA export protein antibody mRNA-associated protein mrnp 41 antibody MRNP 41 antibody MRNP41 antibody RAE 1 antibody RAE1 (RNA export 1 S.pombe) homolog antibody rae1 antibody RAE1 homolog antibody Rae1 protein homolog antibody RAE1 RNA export 1 homolog (S. pombe) antibody RAE1 RNA export 1 homolog antibody RAE1L_HUMAN antibody RNA export 1 antibody RNA export 1 homolog antibody
Abbreviation
RAE1, MRNP41
Swiss Prot
P78406 Human, Q8C570 Mouse, Q3SWS8 Rat
Cellular Locus
Cytoplasm, Nucleus, Cytoplasm, cytoskeleton, spindle pole, Nucleus envelope.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Rae1 aa 319-368 / 368.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
PC-3, mouse testis tissue, rat testis tissue, LOVO, MCF-7, PC-3M.
Concentration
1 mg/mL
Dilution
WB: 1:500-1,000;IF-Cell: 1:50-1:200;FC: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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