RAB7 Rabbit Polyclonal Antibody

CAT: 0992-ER1802-53Size: 100 µLDry Ice: NoHazardous: No
CAT#:0992-ER1802-53Size:100 µL
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Description
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the Ral/Rec, Rap, R-Ras, and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the Sec4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. Several members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.
CAS Number
9007-83-4
Product Name Alternative
CMT2B antibody PRO2706 antibody PSN antibody RAB7, member RAS oncogene family antibody RAB7A antibody RAB7A, member RAS oncogene family antibody RAB7A_HUMAN antibody Ras associated protein RAB7 antibody Ras related protein Rab7 antibody Ras related protein Rab7a antibody Ras-related protein Rab-7a antibody
Abbreviation
RAB7A
Swiss Prot
P51149 Human, P51150 Mouse, P09527 Rat
Cellular Locus
Endosome. Lysosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human RAB7 aa 43-200 / 207.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
MCF-7, rat brain tissue, human brain tissue, human tonsil tissue, human liver tissue, human colon cancer tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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