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iNOS Rabbit Polyclonal Antibody

CAT: 0992-ER1706-89Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1706-89Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nitric oxide (NO) has a broad range of biological activities and has been implicated in signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. The inducible form of NOS, NOS2 (also designated iNOS), is Ca2+-independent and is expressed in a broad range of cell types.
CAS Number
9007-83-4
Product Name Alternative
HEP-NOS antibody Hepatocyte NOS antibody HEPNOS antibody inducible antibody Inducible nitric oxide synthase antibody Inducible NO synthase antibody Inducible NOS antibody iNOS antibody MAC NOS antibody Macrophage NOS antibody Nitric oxide synthase 2 inducible antibody Nitric oxide synthase 2 inducible macrophage antibody nitric oxide synthase 2A (inducible, hepatocytes) antibody Nitric oxide synthase antibody Nitric oxide synthase inducible antibody nitric oxide synthase, macrophage antibody NOS 2 antibody NOS antibody Nos II antibody NOS type II antibody nos2 antibody NOS2_HUMAN antibody NOS2A antibody NOS2A, Inducible, Hepatocyte antibody Peptidyl-cysteine S-nitrosylase NOS2 antibody
Abbreviation
HEP-NOS, Inducible NOS, iNOS, NOS2, NOS2A
Swiss Prot
P35228 Human, P29477 Mouse
Cellular Locus
Cytoskeleton, Nucleus, Cytosol.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Chicken
Immunogen
Synthetic peptide within human iNOS aa 1,104-1,153 / 1,153.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, FC, WB, IHC-Fr
Positive Control
RAW264.7 treated with 1μg/mL LPS for 24 hours whole cell lysate, RAW264.7 whole cell lysate, HeLa cell lysate, A549 cell lysate, A549, LOVO.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100 ;IHC-Fr:1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 131 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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