Products for Research Use Only
RegisterLogin

HMGB2 Rabbit Polyclonal Antibody

CAT: 0992-ER1706-52Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER1706-52Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone.
CAS Number
9007-83-4
Product Name Alternative
C80539 antibody High mobility group (nonhistone chromosomal) protein 2 antibody High mobility group box 2 antibody High mobility group protein 2 antibody High mobility group protein B2 antibody HMG 2 antibody HMG B2 antibody HMG-2 antibody HMG2 antibody HMGB2 antibody HMGB2_HUMAN antibody
Abbreviation
HMG-2, HMGB2, HMG2
Swiss Prot
P26583 Human, P30681 Mouse, P52925 Rat
Cellular Locus
Secreted. Nucleus. Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human HMGB2 aa 22-172.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Mouse testis tissue, LOVO, SH-SY5Y, rat brain tissue, human tonsil tissue, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 24 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA721925HMGB2 Recombinant Rabbit Monoclonal Antibody [JE52-82]
EM1902-06HMGB2 Mouse Monoclonal Antibody [10D1]
ER0913HMGB1 Rabbit Polyclonal Antibody
R1309-12HMGB1 Rabbit Polyclonal Antibody
HA751012HMGA2 Recombinant Rabbit monoclonal Antibody
HA750011HMGB1 Recombinant Rabbit monoclonal Antibody
ER1901-73GABARAPL2 Rabbit Polyclonal Antibody
ER2001-53Transferrin Rabbit Polyclonal Antibody
ER1802-12LSD1 Rabbit Polyclonal Antibody
HA500270AIM2 Rabbit Polyclonal Antibody

Alternative Products

CatalogName
TA377134HMGB2 Rabbit Polyclonal Antibody
NBP3-35743-20ulRabbit Polyclonal HMGB2 Antibody
GTR18562761HMGB2 Rabbit Polyclonal Antibody (APC)
GTR18562760HMGB2 Rabbit Polyclonal Antibody (PE)
GTR18476075HMGB2 Rabbit Polyclonal Antibody (BF488)
GTR18476074HMGB2 Rabbit Polyclonal Antibody (BF555)
GTR17803013HMGB2 Rabbit Polyclonal Antibody (Cy3)
GTR18358414HMGB2 Rabbit Polyclonal Antibody (Biotin)

Popular Products