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Cdc25C Rabbit Polyclonal Antibody

CAT: 0992-ER1706-38Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1706-38Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell cycle events are regulated by the sequential activation and deactivation of cyclin-dependent kinases (Cdks), including Cdk2 and Cdc2. Cdk2 in complexes with cyclin E and cyclin A appears necessary for the onset and progression of DNA replication, while the Cdc2 kinase in complexes with cyclin A or cyclin B is required for the initiation of cell division. Wee 1 has been identified as a protein kinase that suppresses the entry into mitosis by mediating inhibiting tyrosine phosphorylation of Cdc2 p34. In contrast, members of the Cdc25 family of protein phosphatases function as mitotic activators by dephosphorylation of Cdc2 p34 on regulatory tyrosine and possibly threonine residues. The Cdc25 gene family consists of at least three members that share approximately 40% identity in their most conserved carboxy-terminal sequences.
CAS Number
9007-83-4
Product Name Alternative
CDC 25 antibody Cdc 25C antibody CDC25 antibody CDC25C antibody Cell division cycle 25 homolog C antibody Cell division cycle 25C antibody Cell division cycle 25C protein antibody Dual specificity phosphatase Cdc25C antibody M phase inducer phosphatase 3 antibody M-phase inducer phosphatase 3 antibody Mitosis inducer CDC25 antibody MPIP3 antibody MPIP3_HUMAN antibody Phosphotyrosine phosphatase antibody PPP1R60 antibody protein phosphatase 1, regulatory subunit 60 antibody
Abbreviation
CDC25C
Swiss Prot
P30307 Human, P48967 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminal human Cdc25C.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Human skin tissue lysate, A431, HUVEC, LOVO, rat brain tissue, human placenta tissue, mouse uterus tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:500-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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