Cdc25C Rabbit Polyclonal Antibody

Cdc25C Rabbit Polyclonal Antibody

• Description: Cell cycle events are regulated by the sequential activation and deactivation of cyclin-dependent kinases (Cdks), including Cdk2 and Cdc2. Cdk2 in complexes with cyclin E and cyclin A appears necessary for the onset and progression of DNA replication, while the Cdc2 kinase in complexes with cyclin A or cyclin B is required for the initiation of cell division. Wee 1 has been identified as a protein kinase that suppresses the entry into mitosis by mediating inhibiting tyrosine phosphorylation of Cdc2 p34. In contrast, members of the Cdc25 family of protein phosphatases function as mitotic activators by dephosphorylation of Cdc2 p34 on regulatory tyrosine and possibly threonine residues. The Cdc25 gene family consists of at least three members that share approximately 40% identity in their most conserved carboxy-terminal sequences.
• Product Name Alternative: CDC 25 antibody Cdc 25C antibody CDC25 antibody CDC25C antibody Cell division cycle 25 homolog C antibody Cell division cycle 25C antibody Cell division cycle 25C protein antibody Dual specificity phosphatase Cdc25C antibody M phase inducer phosphatase 3 antibody M-phase inducer phosphatase 3 antibody Mitosis inducer CDC25 antibody MPIP3 antibody MPIP3_HUMAN antibody Phosphotyrosine phosphatase antibody PPP1R60 antibody protein phosphatase 1, regulatory subunit 60 antibody
• Abbreviation: CDC25C
• CAS Number: 9007-83-4
• Swiss Prot: P30307 Human, P48967 Mouse
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within C-terminal human Cdc25C.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: Human skin tissue lysate, A431, HUVEC, LOVO, rat brain tissue, human placenta tissue, mouse uterus tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;IF-Cell: 1:500-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 53 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No