Products for Research Use Only
RegisterLogin

PHF10 Rabbit Polyclonal Antibody

CAT: 0992-ER1511-14Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER1511-14Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
CAS Number
9007-83-4
Product Name Alternative
BAF45a antibody BRG1-associated factor 45a antibody FLJ10975 antibody MGC111009 antibody PHD finger protein 10 antibody PHD finger protein 10, isoform a antibody PHD zinc finger protein XAP135 antibody Phf10 antibody PHF10_HUMAN antibody XAP135 antibody
Abbreviation
BAF45a
Swiss Prot
Q8WUB8 Human, Q9D8M7 Mouse, Q4V7A6 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human PHF10 aa 172-374 / 498.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela, rat testis tissue, human tonsil tissue, human liver cancer tissue, human kidney tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 56 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA500478PHF11 Rabbit Polyclonal Antibody
ER1901-73GABARAPL2 Rabbit Polyclonal Antibody
ER2001-53Transferrin Rabbit Polyclonal Antibody
ER1802-12LSD1 Rabbit Polyclonal Antibody
HA500270AIM2 Rabbit Polyclonal Antibody
HA500595TMEM184A Rabbit polyclonal Antibody
HA500594HERC6 Rabbit polyclonal Antibody
HA500591COL4A3 Rabbit polyclonal Antibody
HA500589BAHD1 Rabbit polyclonal Antibody
HA500587OTULIN Rabbit polyclonal Antibody

Alternative Products

CatalogName
GTR18113989-01PHF10 Rabbit Polyclonal Antibody
NBP2-33759Rabbit Polyclonal PHF10 Antibody
GTR18533970PHF10 Rabbit Polyclonal Antibody (Biotin)
GTR18533967PHF10 Rabbit Polyclonal Antibody (FITC)
GTR18533966PHF10 Rabbit Polyclonal Antibody (HRP)
GTR18747531PHF10 Rabbit Polyclonal Antibody (Fluoro594)
MBS8570148-01PHF10 Polyclonal Antibody
GTR18533969PHF10 Rabbit Polyclonal Antibody (Cy3)
GTR18533965PHF10 Rabbit Polyclonal Antibody (APC)

Popular Products