Products for Research Use Only
RegisterLogin

Cyclin D1 Rabbit Polyclonal Antibody

CAT: 0992-ER0722Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2Product image 3
1 / 3
CAT#:0992-ER0722Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cyclins function as regulators of CDKs (Cyclin-dependent kinase). Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Cyclin D1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. Immunohistochemical staining of cyclin D1 antibodies is used to diagnose mantle cell lymphoma. Cyclin D1 has been found to be overexpressed in breast carcinoma. Its potential use as a biomarker was suggested.
CAS Number
9007-83-4
Product Name Alternative
AI327039 antibody B cell CLL/lymphoma 1 antibody B cell leukemia 1 antibody B cell lymphoma 1 protein antibody B-cell lymphoma 1 protein antibody BCL 1 antibody BCL-1 antibody BCL-1 oncogene antibody BCL1 antibody BCL1 oncogene antibody ccnd1 antibody cyclind1 antibody CCND1/FSTL3 fusion gene, included antibody CCND1/IGHG1 fusion gene, included antibody CCND1/IGLC1 fusion gene, included antibody CCND1/PTH fusion gene, included antibody CCND1_HUMAN antibody cD1 antibody Cyl 1 antibody D11S287E antibody G1/S specific cyclin D1 antibody G1/S-specific cyclin-D1 antibody Parathyroid adenomatosis 1 antibody PRAD1 antibody PRAD1 oncogene antibody U21B31 antibody
Abbreviation
CCND1
Swiss Prot
P24385 Human, P25322 Mouse, P39948 Rat
Cellular Locus
Nucleus, Cytoplasm, Nucleus membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Mouse Cyclin D1 aa 1-50 / 295.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Mouse brain tissue lysates, human tonsil tissue, human liver carcinoma tissue, A431.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IHC-P: 1:200 ;FC: 1ug/mL
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 34 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
ET1601-31Cyclin D1 Recombinant Rabbit Monoclonal Antibody [SA38-08]
HA721322Cyclin D1 Recombinant Rabbit Monoclonal Antibody [PD01-64]
ET1601-31TRAnti-Cyclin D1 Antibody [SA38-08]
HA500325Cyclin D2 Rabbit Polyclonal Antibody
HA500287Cyclin A1 Rabbit Polyclonal Antibody
R1308-13Cyclin B1 Rabbit Polyclonal Antibody
ET1612-8Cyclin A1+ Cyclin A2 Recombinant Rabbit Monoclonal Antibody [SD2053]
HA751308Cyclin T1 Recombinant Rabbit monoclonal Antibody
HA751602Cyclin D2 Recombinant Rabbit monoclonal Antibody
HA750288Cyclin A2 Recombinant Rabbit monoclonal Antibody

Alternative Products

CatalogName
E53P03198Cyclin A Rabbit Polyclonal Antibody
NBP2-56867-25ulRabbit Polyclonal Cyclin B1 Antibody
MBS9466294-01Cyclin A2 Rabbit Polyclonal Antibody
APRab03369-01Cyclin A1 Rabbit Polyclonal Antibody
APRab09588-01Cyclin C Rabbit Polyclonal Antibody
APRab09605-01Cyclin M2 Rabbit Polyclonal Antibody
AF6630Cyclin D2 Rabbit Polyclonal Antibody
NBP3-16995-100ulRabbit Polyclonal Cyclin A1 Antibody
NBP3-17238-25ulRabbit Polyclonal Cyclin T1 Antibody
NBP2-98961-50ulRabbit Polyclonal Cyclin B2 Antibody

Popular Products