CD166 Mouse Monoclonal Antibody [5-5]

• Description:

  Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts . Promotes T-cell activation and proliferation via its interactions with CD6 . Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 . Mediates homotypic interactions with cells that express ALCAM . Required for normal hematopoietic stem cell engraftment in the bone marrow . Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction . Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions . Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).

• Product Name Alternative:

  Activated leukocyte cell adhesion molecule antibody ALCAM antibody ALCAM protein antibody CD 166 antibody CD166 antibody CD166 antigen antibody CD166_HUMAN antibody FLJ3851 antibody FLJ38514 antibody MEMD antibody MGC71733 antibody

• Abbreviation:

  CD166 antigen,CD166,Activated leukocyte cell adhesion molecule,ALCAM

• Swiss Prot:

  Q13740 Human

• Cellular Locus:

  Cell membrane, Cell projection, Membrane, Secreted

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within human CD166 aa 1-300.

• Isotype:

  IgG1

• Conjugation:

  Non-conjugated

• Type:

  Mouse monoclonal Antibody

• Applications:

  WB, IHC-P, IF-Cell, FC

• Positive Control:

  PC-3M cell lysate, A549 cell lysate, SHSY5Y cell lysate, A431cells, Huvec celles, human liver tissue, THP-1 cells.

• Concentration:

  2 mg/mL

• Dilution:

  WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 65 kDa.

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4