CD166 Recombinant Rabbit Monoclonal Antibody [JE57-47]

• Description:

  CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. It is also called CD166 (cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. Some literature sources have also cited it as the CD6 ligand (CD6L). It is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 protein expression is reported to be upregulated in a cell line deriving from a metastasizing melanoma. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.

• Product Name Alternative:

  Activated leukocyte cell adhesion molecule antibody ALCAM antibody ALCAM protein antibody CD 166 antibody CD166 antibody CD166 antigen antibody CD166_HUMAN antibody FLJ3851 antibody FLJ38514 antibody MEMD antibody MGC71733 antibody

• Abbreviation:

  ALCAM, MEMD

• Swiss Prot:

  Q13740 Human, Q61490 Mouse, O35112 Rat

• Cellular Locus:

  Cell membrane, Cell projection, axon, dendrite; Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within

• Isotype:

  IgG

• Clone:

  JE57-47

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P, FC, IHC-Fr

• Positive Control:

  U-2 OS cell lysate, A549 cell lysate, SH-SY5Y cell lysate, Mouse brain tissue lysate, Mouse liver tissue lysate, Rat brain tissue lysate, Rat liver tissue lysate, SH-SY5Y, human liver tissue, human stomach tissue, mouse liver tissue, mouse stomach tissue, rat liver tissue, rat stomach tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000 ;IHC-P: 1:200 ;FC: 1:1,000 ;IHC-Fr: 1:200

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 65 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3