TIE-1 Rabbit Polyclonal Antibody

• Description:

  Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 also known as TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene. TIE1 is a cell surface protein expressed exclusively in endothelial cells, however it has also been shown to be expressed in immature hematopoietic cells and platelets. TIE1 upregulates the cell adhesion molecules (CAMs) VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosis.

• Product Name Alternative:

  JKT 14 antibody JTK14 antibody TIE antibody Tie1 antibody TIE1_HUMAN antibody Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1 antibody Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains antibody Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody Tyrosine protein kinase receptor Tie 1 antibody Tyrosine-protein kinase receptor Tie-1 antibody

• Abbreviation:

  TIE-1

• Swiss Prot:

  P35590 Human

• Cellular Locus:

  Cell membrane. Membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within Human TIE-1 aa 23-72 / 1,138.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell

• Positive Control:

  K562, HepG2, SW620.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 125 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4