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Tie-1 Polyclonal Antibody

CAT: 0965-JOT-AP09015-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09015-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TIE1.
CAS Number
9007-83-4
Synonyms
TIE1; TIE; Tyrosine-protein kinase receptor Tie-1
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TIE1. AA range:851-900
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
125090
Antibody Type
Primary antibody
Isotype
IgG