ESR1 Rabbit Polyclonal Antibody
CAT:
992-0803-1
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ESR1 Rabbit Polyclonal Antibody
- Description: Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ESR1 (EStrogen Receptor 1). The estrogen receptor (ESR) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The ESR1 protein localizes to the nucleus where it may forms a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
- Product Name Alternative: DKFZp686N23123 antibody ER alpha antibody ER antibody ER-alpha antibody Era antibody ESR antibody ESR1 antibody ESR1_HUMAN antibody ESRA antibody Estradiol receptor antibody Estrogen nuclear receptor alpha antibody Estrogen receptor 1 antibody Estrogen receptor alpha 3*,4,5,6,7*/822 isoform antibody Estrogen receptor alpha antibody Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform antibody Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform antibody Estrogen receptor alpha delta 4 +49 isoform antibody Estrogen receptor alpha delta 4*,5,6,7*/654 isoform antibody Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform antibody Estrogen receptor alpha E1 E2 1 2 antibody Estrogen receptor alpha E1 N2 E2 1 2 antibody Estrogen receptor antibody ESTRR antibody NR3A1 antibody Nuclear receptor subfamily 3 group A member 1 antibody
- Abbreviation: ER,ESR1
- CAS Number: 9007-83-4
- Swiss Prot: P03372 Human
- Cellular Locus: Nucleus, Cytoplasm, Cell membrane.
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Recombinant protein within C terminal human estrogen receptor.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IF-Cell, IHC-P
- Positive Control: MCF-7, human breast tissue, SK-Br-3.
- Concentration: 1 mg/mL
- Dilution: WB: 1:2,000 ;IHC-P: 1:100 ;IF-Cell: 1:50
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 66 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Recombinant Antibody: No