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(R) -RO5263397

CAT: 0804-HY-W634602-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W634602-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -RO5263397 is a TAAR 1 agonist that demonstrates efficacy in reducing cocaine-mediated behaviors, including cocaine-induced behavioral sensitization, cue- and cocaine prime-induced reinstatement of cocaine-seeking behavior, and the expression of conditioned place preference.
CAS Number
1357266-80-8
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
Trace Amine-associated Receptor (TAAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-ro5263397.html
Smiles
CC1=C(C=CC=C1[C@@H]2COC(N)=N2)F
Molecular Formula
C10H11FN2O
Molecular Weight
194.21
Precautions
P264-P270-P330
References & Citations
[1]Effects of the trace amine-associated receptor 1 agonist RO5263397 on abuse-related effects of cocaine in rats
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

(R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-amine
CAS Number1357266-80-8
PubChem CID66705786
IUPAC Name(4R)-4-(3-fluoro-2-methylphenyl)-4,5-dihydro-1,3-oxazol-2-amine
Molecular FormulaC10H11FN2O
Molecular Weight194.21
XLogP1.4
Topological Polar Surface Area47.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count14
Formal Charge0
Complexity244
SMILES
CC1=C(C=CC=C1F)[C@@H]2COC(=N2)N
InChI
InChI=1S/C10H11FN2O/c1-6-7(3-2-4-8(6)11)9-5-14-10(12)13-9/h2-4,9H,5H2,1H3,(H2,12,13)/t9-/m0/s1
InChIKey
IOHOUWIYOVWGHV-VIFPVBQESA-N
Chemical Structure
2D Structure
2D structure of (R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-amine
CAS: 1357266-80-8
CID: 66705786
Formula: C10H11FN2O
MW: 194.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight194.21
XLogP31.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass194.08554114
Monoisotopic Mass194.08554114
Topological Polar Surface Area47.6 Ų
Heavy Atom Count14
Formal Charge0
Complexity244
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BA5825-100RO5263397
MBS5802157(4R)-RO5263397
M33108-01(4R) -RO5263397

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