HG-7-86-01

HG-7-86-01

• CAS Number: 1258391-14-8
• UNSPSC Description: HG-7-86-01 (Compound 26) is type II tyrosine kinase inhibitor. HG-7-86-01 has anti-proliferative activity[1].
• Target Antigen: Bcr-Abl
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hg-7-86-01.html
• Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1CC1)NC2=NC3=CC=C(C4=CC=CC(C(NC5=CC(N6C=NC(C)=C6)=CC(C(F)(F)F)=C5)=O)=C4)N=C3S2
• Molecular Weight: 562.57
• References & Citations: [1]Choi HG, et al. Development of 'DFG-out' inhibitors of gatekeeper mutant kinases. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5297-302.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported