Cynomolgus IFN-alpha/beta R1 Protein, His Tag (MALS verified)

Cynomolgus IFN-alpha/beta R1 Protein, His Tag (MALS verified)

• Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
• Description: Cynomolgus IFN-alpha/beta R1 Protein, His Tag (IF1-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 25 - Lys 437 (Accession # A0A7N9D7J0-1).
• Specifications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.3 kDa. The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Ala 25 - Lys 437
• Host: HEK 293
• Target: IFN-alpha/beta R1
• Conjugation: Unconjugated
• Tag: C-10×His
• Source: Cynomolgus
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 1.0 EU per μg
• Purity: 90%
• Bioactivity: Immobilized Human IFN-alpha 1, Fc Tag (Cat. No. IFA-H5258) at 5 μg/mL (100 μL/well) can bind Cynomolgus IFN-alpha/beta R1 Protein, His Tag (Cat. No. IF1-C52H3) with a linear range of 5-78 ng/mL (QC tested).
• Format: Powder
• Buffer: PBS, pH7.4
• Additives: Trehalose
• Molecular Weight: 49.3 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C