PE-Labeled Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Tetramer Protein

PE-Labeled Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Tetramer Protein

• Background: Tyrosine phosphatase that acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.In addition to its tyrosine phosphatase activity has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor
• Description: PE-Labeled Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Tetramer Protein (HLP-HP2Hb) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & ALDVYNGLL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & ALDVYNGLL).
• Specifications: PE-Labeled Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Tetramer Protein is assembled by biotinylated monomer and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Complex Protein is produced by co-expression of HLA and B2M loaded with PAP peptide. Biotinylated Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
• Expression Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & ALDVYNGLL peptide
• Host: HEK 293
• Target: HLA-A*0201 & B2M & PAP (ALDVYNGLL)
• Conjugation: PE Labeled
• Tag: C-10×His
• Source: Human
• Stability: The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
• Endotoxin: 1.0 EU per μg
• Bioactivity: Immobilized PE-Labeled Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Tetramer Protein (Cat. No. HLP-HP2Hb) at 1 μg/mL (100 μL/well) can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-2 ng/mL (QC tested).
• Format: Liquid
• Buffer: PBS, 1% BSA, pH7.4
• Additives: Trehalose
• Molecular Weight: 36.3 kDa and 11.7 kDa
• Shipping Conditions: Dry ice
• Storage Conditions: -70°C, aviod light