PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein
CAT:
716-HLA-HP2H5-200ug
Size:
200 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein
- Background: Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms and binds copper, nickel, fatty acids, and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. The Human HLA-A*0201 AFP (FMNKFIYEI) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and FMNKFIYEI peptide of the AFP.
- Description: PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein (HLA-HP2H5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & FMNKFIYEI peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & FMNKFIYEI).
- Specifications: PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein is assembled by biotinylated monomer (HLA-H82E3) and PE-labeled streptavidin. Biotinylated Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Complex Protein is produced by co-expression of HLA and B2M loaded with AFP peptide. Biotinylated Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
- Expression Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & FMNKFIYEI peptide
- Host: HEK 293
- Target: HLA-A*0201 & B2M & AFP (FMNKFIYEI)
- Conjugation: PE Labeled
- Tag: C-10×His
- Source: Human
- Stability: The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
- Endotoxin: 1.0 EU per μg
- Bioactivity: Immobilized PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein (Cat. No. HLA-HP2H5) at 1 μg/mL (100 μL/well) can bind Anti-HLA-A2&AFP Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).
- Format: Liquid
- Buffer: PBS, 1% BSA, pH7.4
- Additives: Trehalose
- Molecular Weight: 36.3 kDa and 11.7 kDa
- Shipping Conditions: Dry ice
- Storage Conditions: -70°C, aviod light