FKBP51-Hsp90-IN-1

FKBP51-Hsp90-IN-1

• CAS Number: 433313-64-5
• UNSPSC Description: FKBP51-Hsp90-IN-1 (Compound D10) is a selective inhibitor of the FKBP51-Hsp90 protein-protein interaction, with an IC50 value of 0.1 μM against FKBP51. FKBP51-Hsp90-IN-1 can be used in the research of stress-related diseases, Alzheimer's disease, and metabolic disorders[1].
• Target Antigen: FKBP; HSP
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Metabolic Disease; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/fkbp51-hsp90-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C(C(C(N)=O)=C(S1)NC(CCCC(NC2=C(C(C)=C(S2)C)C(N)=O)=O)=O)C
• Molecular Weight: 436.55
• References & Citations: [1]Wang L, et al. Structure-based discovery of small molecule inhibitors of FKBP51-Hsp90 protein-protein interaction. Eur J Med Chem. 2024;270:116356.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported