Products for Research Use Only
RegisterLogin

1,2,4-Trihydroxybenzene

CAT: 0804-HY-W010451-01Size: 25 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W010451-01Size:25 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
1,2,4-Trihydroxybenzene (Hydroxyhydroquinone) is an ER stress inducer that targets proteins such as PKR-like ER kinase PERK to induce cytotoxicity. 1,2,4-Trihydroxybenzene selectively activates eIF2α phosphorylation, activates the PERK-eIF2α signaling pathway and induces stress granule formation. 1,2,4-Trihydroxybenzene subsequently exacerbates oxidative stress and causes DNA double-strand breaks, destroying organelles such as mitochondria and ER, and inducing cell death. 1,2,4-Trihydroxybenzene also has the potential to exhibit anti-tumor effect, increase blood pressure, and relieve spasm[1][2][3][4].
CAS Number
533-73-3
Product Name Alternative
Hydroxyhydroquinone
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335
Target
Apoptosis; Eukaryotic Initiation Factor (eIF) ; PERK; Potassium Channel
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/1-2-4-trihydroxybenzene.html
Purity
99.32
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(O)C=C1O
Molecular Formula
C6H6O3
Molecular Weight
126.11
Precautions
H302, H315, H318, H335
References & Citations
2+
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
EIF2

Related Products

CatalogName
HY-W017850-011,5,2,4-Dioxadithiane 2,2,4,4-tetraoxide
HY-77024-012,2,2-Trifluoro-1- (4'- (methylsulfonyl) -[1,1'-biphenyl]-4-yl) ethanone
HY-W0123831- (2,4-Difluorophenyl) -2- (1H-1,2,4-triazol-1-yl) ethanone
HY-155764COX-1/2-IN-4
HY-E70191β-1,4-Galactosyltransferase 2
HY-128435-012,4'-Dihydroxybenzophenone-1
HY-W0170871,2,4-Trimethoxybenzene
HY-Y0219-011,2,4-Triazole
HY-146253CDK1/2/4-IN-1
HY-W012383R-011- (2,4-Difluorophenyl) -2- (1H-1,2,4-triazol-1-yl) ethanone (Standard)

Alternative Products

CatalogName
AR-P01807-011,2,4-Trihydroxybenzene
T245651,2,3-Trihydroxybenzene 99%
61888959Pyrogallol (1,2,3-Trihydroxybenzene)
PC6880Pyrogallol (1, 2, 3-Trihydroxybenzene)
FUD80435-013,4,5-Trihydroxybenzene-1-sulfonamide
RG-E242726-012,4,6-trihydroxybenzene-1,3,5-tricarbaldehyde
ICA34312-014,5,6-Trihydroxybenzene-1,3-dicarbaldehyde
abx1880911,3,5-Trihydroxybenzene Dihydrate
MBS6038637-01Phloroglucinol, Anhydrous (1,3,5-Trihydroxybenzene)
2457-01PHLOROGLUCINOL, AR GRADE (1,3,5, Trihydroxybenzene)

Popular Products