PROTAC ATR degrader-1
CAT:
804-HY-157764
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC ATR degrader-1
- CAS Number: 2925916-30-7
- UNSPSC Description: PROTAC ATR degrader-1 (compound ZS-7) is a potent PROTAC degrader of ataxia telangiectasia and Rad3-related (ATR), with DC50 of 0.53 μM. PROTAC ATR degrader-1 plays an importnt role in cancer research[1].
- Target Antigen: ATM/ATR; PROTACs
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR;PROTAC
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-atr-degrader-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(N1C2C(NC(CC2)=O)=O)C3=C(C=CC=C3C1=O)NC(CCCCCCCN4N=NC(CCC(N=[S@](C5(C6=CC(N7[C@@H](COCC7)C)=NC(C8=CC=NC9=C8C=CN9)=N6)CC5)(C)=O)=O)=C4)=O
- Molecular Weight: 933.05
- References & Citations: [1]Lei Huang, et al. Discovery of the first ataxia telangiectasia and Rad3-related (ATR) degraders for cancer treatment.Eur J Med Chem. 2024 Feb 1:267:116159.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported