Choline tosylate

Choline tosylate

• CAS Number: 55357-38-5
• UNSPSC Description: Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG)[1][2].
• Target Antigen: Phospholipase
• Type: Biochemical Assay Reagents
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/choline-tosylate.html
• Purity: 99.95
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC1=CC=C(C=C1)S(=O)(=O)[O-].C[N+](C)(C)CCO
• Molecular Weight: 275.37
• References & Citations: [1]Yu L, et al. The interaction of phospholipase A2 with phospholipid analogues and inhibitors. J Biol Chem. 1990 Feb 15;265(5):2657-64.|[2]Trousil S. Choline Kinase Inhibition as a Treatment Strategy of Cancers with Deregulated Lipid Metabolism. Imperial College London, 2014.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Phase 4