Choline tosylate

• UNSPSC Description:

  Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG)[1][2].

• Target Antigen:

  Phospholipase

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/choline-tosylate.html

• Purity:

  99.95

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC1=CC=C(C=C1)S(=O)(=O)[O-].C[N+](C)(C)CCO

• Molecular Weight:

  275.37

• References & Citations:

  [1]Yu L, et al. The interaction of phospholipase A2 with phospholipid analogues and inhibitors. J Biol Chem. 1990 Feb 15;265(5):2657-64.|[2]Trousil S. Choline Kinase Inhibition as a Treatment Strategy of Cancers with Deregulated Lipid Metabolism. Imperial College London, 2014.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Phase 4

• CAS Number:

  55357-38-5