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Tetomilast

CAT: 0804-HY-105092-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105092-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the research of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD) .
CAS Number
145739-56-6
Product Name Alternative
OPC-6535
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tetomilast.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCOC1=C(OCC)C=CC(C2=NC(C3=CC=CC(C(O)=O)=N3)=CS2)=C1
Molecular Formula
C19H18N2O4S
Molecular Weight
370.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Ichikawa H, Okamoto S, Kamada N, et al. Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice. Inflamm Bowel Dis. 2008;14 (11) :1483-1490.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
PDE4

Alternative Products

CatalogName
OR1035880Tetomilast

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