11-Hydroxytephrosin

• Description :

  11-Hydroxytephrosin is a potent inhibitor of NF-kappaB. NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation[1].

• CAS Number :

  [72458-85-6]

• UNSPSC :

  12352005

• Target :

  NF-κB

• Type :

  Natural Products

• Related Pathways :

  NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/11-hydroxytephrosin.html

• Purity :

  98.0

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC(O)=C14

• Molecular Formula :

  C23H22O8

• Molecular Weight :

  426.42

• References & Citations :

  [1]Dat NT, et al. Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod. 2008;71 (10) :1696-1700.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported