11-Hydroxytephrosin

• UNSPSC Description:

  11-Hydroxytephrosin is a potent inhibitor of NF-kappaB. NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation[1].

• Target Antigen:

  NF-κB

• Type:

  Natural Products

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/11-hydroxytephrosin.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC(O)=C14

• Molecular Weight:

  426.42

• References & Citations:

  [1]Dat NT, et al. Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod. 2008;71(10):1696-1700.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  72458-85-6