AP1867-2-(carboxymethoxy)
CAT:
804-HY-114420-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AP1867-2-(carboxymethoxy)
- CAS Number: 2230613-03-1
- UNSPSC Description: AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules[1].
- Target Antigen: FKBP; Ligands for Target Protein for PROTAC
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-fkbp12-ligand-1.html
- Purity: 99.85
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC=C3OCC(O)=O)CCC4=CC=C(OC)C(OC)=C4
- Molecular Weight: 693.78
- References & Citations: [1]Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported