AP1867

• UNSPSC Description:

  AP1867 is a synthetic FKBP12F36V-directed ligand[1].

• Target Antigen:

  FKBP

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/AP1867.html

• Purity:

  99.43

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  COC1=CC=C(CC[C@@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)C4=CC=CC(OCC(O)=O)=C4)C=C1OC

• Molecular Weight:

  693.78

• References & Citations:

  [1]Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.|[2]Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  195514-23-9