(E) -Ferulic acid-d3

CAT: 0804-HY-N0060BS-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0060BS-01Size:1 mg
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Description
(E) -Ferulic acid-d3 is the deuterium labeled (E) -Ferulic acid. (E) -Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E) -Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E) -Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E) -Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].
CAS Number
[860605-59-0]
Product Name Alternative
(E) -Coniferic acid-d3
UNSPSC
12352005
Target
Bcl-2 Family; Endogenous Metabolite; Ferroptosis; β-catenin
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Stem Cell/Wnt
Field of Research
Cancer
Purity
99.76
Solubility
DMSO : 100mg/mL (ultrasonic)
Smiles
O=C(O)/C=C/C1=CC=C(O)C(OC([2H])([2H])[2H])=C1
Molecular Formula
C10H7D3O4
Molecular Weight
197.20
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Fong Y, et al. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med. 2016 Oct 1;11:45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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