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(E) -Ferulic acid

CAT: 0804-HY-N0060B-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-N0060B-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E) -Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E) -Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E) -Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E) -Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.
CAS Number
537-98-4
Product Name Alternative
(E) -Coniferic acid
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Bcl-2 Family; Endogenous Metabolite; Ferroptosis; β-catenin
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-ferulic-acid.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C/C1=CC=C(O)C(OC)=C1
Molecular Formula
C10H10O4
Molecular Weight
194.19
Precautions
H315, H319, H335
References & Citations
[1]Fong Y, et al. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med. 2016 Oct 1;11:45.|[2]Ogbuta A A, et al. Protective Effects of Trans-Ferulic acid on Tamoxifen Induced Heptatic and Renal Oxidative Stress in Male Wister Albino Rat. Journal of Applied Sciences and Environmental Management, 2023, 27 (8) : 1727-1732.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Bax; Microbial Metabolite

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CatalogName
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