C3a (70-77) (TFA)

• UNSPSC Description:

  C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a[1][2].

• Target Antigen:

  Complement System

• Type:

  Peptides

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/c3a-70-77-tfa.html

• Purity:

  95.02

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C)NC([C@H](CC(C)C)NC(CNC([C@H](CC(C)C)NC([C@H](CC1=CNC=N1)NC([C@H](CO)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

• Molecular Weight:

  937.96

• References & Citations:

  [1]Payan DG, et al. Modulation of human lymphocyte function by C3a and C3a(70-77). J Exp Med. 1982 Sep 1;156(3):756-65.|[2]Caporale LH, et al. The active site of C3a anaphylatoxin. J Biol Chem. 1980 Nov 25;255(22):10758-63.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported