RegisterLogin

VSP-77

CAT: 0804-HY-133559Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-133559Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
VSP-77 is an orally active PPARĪ³ agonist. VSP-77 selectively upregulates the expression of insulin sensitivity-related genes (Glut4 and Adiponectin) by inhibiting CDK5-mediated phosphorylation of PPARĪ³ at Ser-273. VSP-77 significantly improves glucose tolerance, reduces fasting blood glucose and insulin levels in high-fat diet (HFD) -induced diabetic mouse models. VSP-77 can be used for the study of diabetes[1].
CAS Number
[1854008-12-0]
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
ClC1=CC=C(C(CCCCCCC)OCC(O)=O)C=C1
Molecular Formula
C16H23ClO3
Molecular Weight
298.81
References & Citations
[1]Jiang H, et al. Identification and structural insight of an effective PPARĪ³ modulator with improved therapeutic index for anti-diabetic drug discovery. Chem Sci. 2020 Jan 21;11 (8) :2260-2268.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-157726HSD17B13-IN-77
HY-78349-01A 77-01
HY-P5692Maximin 77
HY-136720ZXX2-77
HY-169411Ī±-Glucosidase-IN-77
HY-169014HDAC-IN-77
HY-163080SSelenium-77
HY-18628-01UMI-77
HY-162933AChE-IN-77
HY-157334-01DEG-77

Alternative Products

CatalogName
T205769-01K-lock-VSP-Cit-DUO-5
AS21 4522Anti-VSP | Vegetative storage protein 1
abx680559-01Giardia Lamblia Variant-Specific Surface Protein (VSP) Protein
MBS3604808-01UMI-77
M35259-01AY 77
T24464-01ZXX2-77
6712/5A 77-01
TRC-P215145-250MGPBDE 77
MBS5784578W 77
MBS131177-01D-77

Popular Products