5-O-Methylembelin
CAT:
804-HY-W510159-04
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
5-O-Methylembelin
- CAS Number: 56005-10-8
- UNSPSC Description: 5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9, inducible degrader of the low-density lipoprotein receptor (IDLR), and sterol regulatory element binding protein 2 (SREBP2) mRNA expression[1].
- Target Antigen: PCSK9
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/5-o-methylembelin.html
- Purity: 98.84
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CCCCCCCCCCCC1=C(C(C=C(C1=O)OC)=O)O
- Molecular Weight: 308.41
- References & Citations: [1]Pisey Pel, et al. Isocoumarins and Benzoquinones with Their Proprotein Convertase Subtilisin/Kexin Type 9 Expression Inhibitory Activities from Dried Roots of Lysimachia vulgaris. ACS Omega. 2022 Dec 8;7(50):47296-47305.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported