Products for Research Use Only
RegisterLogin

Cyclamic acid (sodium)

CAT: 0804-HY-W014839-01Size: 5 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W014839-01Size:5 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cyclamic acid sodium (Sodium cyclamate) is a commonly used sweetener. Cyclamic acid sodium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid sodium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid sodium have no carcinogenic effect. In addition, Cyclamic acid sodium has no effect on insulin and glucagon secretion induced by arginine[1][2][3][4][5].
CAS Number
139-05-9
Product Name Alternative
Sodium cyclamate; Cyclohexylsulfamic acid (sodium)
UNSPSC
12352211
Hazard Statement
H302
Target
Apoptosis; Necroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyclamic-acid-sodium.html
Purity
99.43
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=S(NC1CCCCC1)(O[Na])=O
Molecular Formula
C6H12NNaO3S
Molecular Weight
201.22
Precautions
H302
References & Citations
[1]Leban I, et, al. Structures of artificial sweeteners--cyclamic acid and sodium cyclamate with other cyclamates. Acta Crystallogr B. 2007 Jun;63 (Pt 3) :418-25.|[2]Knowles MA, Jani H, Hicks RM. Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate. Carcinogenesis. 1986 May;7 (5) :767-74.|[3]Chen Z, et al. Toxicity of food sweetener-sodium cyclamate on osteoblasts cells. Biochem Biophys Res Commun. 2019 Jan 8;508 (2) :507-511.|[4]Brantom PG, et al. Long-term toxicity of sodium cyclamate in mice. Food Cosmet Toxicol. 1973 Oct;11 (5) :735-46.|[5]Usami M, et al. Effect of cyclamate sodium, saccharin sodium and stevioside on arginine-induced insulin and glucagon secretion in the isolated perfused rat pancreas. Horm Metab Res. 1980 Dec;12 (12) :705-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W014839S1Cyclamic acid-d4 (sodium)
HY-W014839SCyclamic acid-d11 (sodium)
HY-B0541-01Cyclamic acid
HY-W719824Cyclamic acid (calcium)
HY-B0541SCyclamic Acid-d11
HY-N15890Tauroisolithocholanoic acid (sodium)
HY-201296ATauroursocholic acid (sodium)
HY-N0060A-01Ferulic acid (sodium)
HY-166087Docosatrienoic acid (sodium)
HY-112540B-01Acetoacetic acid (sodium)

Alternative Products

CatalogName
BUP19518Cyclamic acid sodium
163229-01Cyclamic Acid Sodium Salt
163230Cyclamic Acid-d11 Sodium Salt
007244Cyclamic Acid

Popular Products