MCP-1/CCL2, Mouse (Biotinylated, sf9, His)

• UNSPSC Description:

  MCP-1/CCL2 Protein, Mouse (Biotinylated, sf9, His) is a cytokine belonging to the CC chemokine family that interacts with the CCR2 chemokine receptor on the cell surface to mediate inflammatory immune responses, viral infections, and tumorigenesis. MCP-1/CCL2 Protein, Mouse (Biotinylated, sf9, His) is a biotinylated mouse MCP-1/CCL2 (M1-N148) expressed by  Spodoptera frugiferda(Sf9) with a His tag at the C-terminus[1].

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/mcp-1-ccl2-protein-mouse-biotinylated-sf9-his.html

• Molecular Weight:

  Approximately 27 kDa.

• References & Citations:

  [1]Qiongyu Hao, et al.  CCL2/CCR2 signaling in cancer pathogenesis. Cell Commun Signal. 2020 May 29;18(1):82.|[2]Svetlana M Stamatovic, et al. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab. 2005 May;25(5):593-606.|[3]Rachel N Gomes, et al. Bacterial clearance in septic mice is modulated by MCP-1/CCL2 and nitric oxide. Shock. 2013 Jan;39(1):63-9.|[4]Lijun Zhang, et al. Effect of chemokine CC ligand 2 (CCL2) on α?synuclein?induced microglia proliferation and neuronal apoptosis. Mol Med Rep. 2018 Nov;18(5):4213-4218.

• Shipping Conditions:

  Room temperature