DB-0646

DB-0646

• CAS Number: 2769753-59-3
• UNSPSC Description: DB-0646, a PROTAC, is a multi-kinase degrader[1].
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/db-0646.html
• Smiles: O=C(N1C2CCC(NC2=O)=O)C3=C(OCCCCCN4N=NC(CN5CCN(C6=NC=C(NC7=NC=C8C(N(C)C(N(C9=CC(NC(C%10=CC=CC(C(F)(F)F)=C%10)=O)=CC=C9C)C8)=O)=N7)C=C6)CC5)=C4)C=CC=C3C1=O
• Molecular Weight: 1041.05
• References & Citations: [1]Katherine A Donovan, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183(6):1714-1731.e10.
• Shipping Conditions: Room Temperature