DB-959

• Description:

  DB-959 (PPARδ/γ agonist 1) is a potent PPAR agonist targeting PPARδ/γ. DB-959 improves spatial learning and memory in mice induced by Streptozotocin (HY-13753) and has the potential to improve Alzheimer's disease (AD) .[1].

• Product Name Alternative:

  PPARδ/γ agonist 1

• UNSPSC:

  12352005

• Target:

  PPAR

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/db-959.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C[C@@H]1CCC2=C1C=CC(OCCC3=C(CC)OC(C4=CC=C(OC)C=C4)=N3)=C2

• Molecular Formula:

  C25H27NO5

• Molecular Weight:

  421.49

• References & Citations:

  [1]Tong M, et, al. T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease. J Alzheimers Dis. 2016;51 (1) :123-38.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1257641-15-8]