Products for Research Use Only
RegisterLogin

3-Hydroxykynurenine (Standard)

CAT: 0804-HY-113294R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-113294R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
3-Hydroxykynurenine (Standard) is the analytical standard of 3-Hydroxykynurenine. This product is intended for research and analytical applications. 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis[1].
CAS Number
484-78-6
Product Name Alternative
3-Hydroxy-DL-kynurenine (Standard)
UNSPSC
12352005
Target
Apoptosis; Endogenous Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxykynurenine-standard.html
Purity
99.34
Smiles
O=C(O)C(N)CC(C1=CC=CC(O)=C1N)=O
Molecular Formula
C10H12N2O4
Molecular Weight
224.21
References & Citations
[1]S Okuda, et al. 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity. J Neurochem. 1998 Jan;70 (1) :299-307.|[2]Sarah S Zaher, et al. 3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci. 2011 Apr 22;52 (5) :2640-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported

Chemical Information

3-Hydroxykynurenine

3-hydroxykynurenine is a hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3. It has a role as a human metabolite.

CAS Number484-78-6
PubChem CID89
IUPAC Name2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
Molecular FormulaC10H12N2O4
Molecular Weight224.21
XLogP-2.5
Topological Polar Surface Area127
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count16
Formal Charge0
Complexity282
SMILES
C1=CC(=C(C(=C1)O)N)C(=O)CC(C(=O)O)N
InChI
InChI=1S/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16)
InChIKey
VCKPUUFAIGNJHC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-Hydroxykynurenine
CAS: 484-78-6
CID: 89
Formula: C10H12N2O4
MW: 224.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight224.21
XLogP3-2.5
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass224.07970687
Monoisotopic Mass224.07970687
Topological Polar Surface Area127 Ų
Heavy Atom Count16
Formal Charge0
Complexity282
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-113294-013-Hydroxykynurenine
HY-W6995403-Hydroxykynurenine-O-β-glucoside
HY-113294S3-Hydroxykynurenine-13C3,15N
HY-113294S23-Hydroxykynurenine-13C2,15N (hydrochloride)
HY-15758R-013,3'-Diindolylmethane (Standard)
HY-Y0603R3-Hydroxyacetophenone (Standard)
HY-W047478R3-Methylcarbazole (Standard)
HY-W012815R-013-Methylcatechol (Standard)
HY-W007708R3-Furanmethanol (Standard)
HY-19312R-013-Methyladenine (Standard)

Alternative Products

CatalogName
C274-625UL3'3'-cGAMP Standard, 625UL
C274-125UL3'3'-cGAMP Standard, 125UL
MBS664086-01CA15-3, standard grade
GC0064Standard siRNA Package-A*3
C296-125UL2',3'-cGAMP Standard
LW4112Pastette standard 3.5ml
CALMIX3-500ICP Instrument Check Standard 3
WINE-3Organic Wine Standard 3 - 1ML
PH-BUFF3-500PH 3 Buffer Standard 500mL
07376-12Tweezers, 3 Rubis, standard tip

Popular Products