(E/Z)-Sulindac sulfide
CAT:
804-HY-B1786A-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(E/Z)-Sulindac sulfide
- CAS Number: 32004-67-4
- UNSPSC Description: (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer’s disease[1].
- Target Antigen: Amyloid-β; γ-secretase
- Type: Reference compound
- Related Pathways: Neuronal Signaling;Stem Cell/Wnt
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/e-z-sulindac-sulfide.html
- Purity: 99.88
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C(CC(C(C=C(C=C1)F)=C1C2=CC3=CC=C(C=C3)SC)=C2C)O
- Molecular Weight: 340.419
- References & Citations: [1]Richter L, et al. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported